FBXO32 Protein (His tag)
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- Target See all FBXO32 Proteins
- FBXO32 (F-Box Protein 32 (FBXO32))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This FBXO32 protein is labelled with His tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human F-box protein 32 (FBXO32), transcript variant 2, full length, with N-terminal HIS tag, expressed in E.Coli, 50 μg (full length, N-term HIS tag, transcript variant 2) protein expressed in E.coli.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product FBXO32 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the N-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 50 mM Tris,8M Urea, pH 8.0.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- FBXO32 (F-Box Protein 32 (FBXO32))
- Abstract
- FBXO32 Products
- Synonyms
- MGC56479 Protein, zgc:56479 Protein, Fbx32 Protein, MAFbx Protein, 4833442G10Rik Protein, AI430017 Protein, ATROGIN1 Protein, Gm20361 Protein, Atrogin1 Protein, F-box protein 32 Protein, fbxo32 Protein, FBXO32 Protein, Fbxo32 Protein
- Background
- This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms.
- Molecular Weight
- 24.5 kDa
- NCBI Accession
- NP_680482
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