ERN1 Protein (Myc-DYKDDDDK Tag)
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- Target See all ERN1 Proteins
- ERN1 (Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This ERN1 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human ERN1 / IRE1 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product ERN1 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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Hypothermia and Rewarming Activate a Macroglial Unfolded Protein Response Independent of Hypoxic-Ischemic Brain Injury in Neonatal Piglets." in: Developmental neuroscience, Vol. 38, Issue 4, pp. 277-294, (2016) (PubMed).
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Hypothermia and Rewarming Activate a Macroglial Unfolded Protein Response Independent of Hypoxic-Ischemic Brain Injury in Neonatal Piglets." in: Developmental neuroscience, Vol. 38, Issue 4, pp. 277-294, (2016) (PubMed).
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- Target
- ERN1 (Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1))
- Alternative Name
- Ern1,ire1 (ERN1 Products)
- Synonyms
- IRE1 Protein, IRE1P Protein, IRE1a Protein, hIRE1p Protein, 9030414B18Rik Protein, AI225830 Protein, C85377 Protein, Ire1a Protein, Ire1alpha Protein, Ire1p Protein, RGD1559716 Protein, Ern1 Protein, Ire1 Protein, Ire1b Protein, sb:eu1005 Protein, zgc:109932 Protein, endoplasmic reticulum to nucleus signaling 1 Protein, endoplasmic reticulum to nucleus signaling 2 Protein, endoplasmic reticulum (ER) to nucleus signalling 1 Protein, serine/threonine-protein kinase/endoribonuclease IRE1 Protein, endoplasmic reticulum (ER) to nucleus signalling 2 Protein, ERN1 Protein, ERN2 Protein, Ern1 Protein, LOC524719 Protein, Ern2 Protein, ern1 Protein
- Background
- The protein encoded by this gene is the ER to nucleus signalling 1 protein, a human homologue of the yeast Ire1 gene product. This protein possesses intrinsic kinase activity and an endoribonuclease activity and it is important in altering gene expression as a response to endoplasmic reticulum-based stress signals.
- Molecular Weight
- 109.6 kDa
- NCBI Accession
- NP_001424
- Pathways
- ER-Nucleus Signaling, Unfolded Protein Response
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