EDNRB Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- Target See all EDNRB Proteins
- EDNRB (Endothelin Receptor Type B (EDNRB))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 1
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This EDNRB protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Endothelin B receptor (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product EDNRB Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- EDNRB (Endothelin Receptor Type B (EDNRB))
- Alternative Name
- Endothelin B Receptor (EDNRB Products)
- Synonyms
- ABCDS Protein, ET-B Protein, ET-BR Protein, ETB Protein, ETBR Protein, ETRB Protein, HSCR Protein, HSCR2 Protein, WS4A Protein, Ednra Protein, Etb Protein, ETR-b Protein, ETb Protein, Sox10m1 Protein, EDNRB Protein, abcds Protein, etb Protein, etrb Protein, hscr Protein, hscr2 Protein, endothelin receptor type B Protein, EDNRB Protein, Ednrb Protein, ednrb Protein
- Background
- The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternative splicing and the use of alternative promoters results in multiple transcript variants.
- Molecular Weight
- 46.9 kDa
- NCBI Accession
- NP_000106
- Pathways
- Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process
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