ELAVL1 Protein (Myc-DYKDDDDK Tag)
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- Target See all ELAVL1 Proteins
- ELAVL1 (ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 1 (Hu Antigen R) (ELAVL1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This ELAVL1 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human ELAVL1 / HUR protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product ELAVL1 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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Oncogenic p95HER2 regulates Na+-HCO3- cotransporter NBCn1 mRNA stability in breast cancer cells via 3'UTR-dependent processes." in: The Biochemical journal, Vol. 473, Issue 21, pp. 4027-4044, (2016) (PubMed).
: "Tissue-specific control of brain-enriched miR-7 biogenesis." in: Genes & development, Vol. 27, Issue 1, pp. 24-38, (2013) (PubMed).
: "
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Oncogenic p95HER2 regulates Na+-HCO3- cotransporter NBCn1 mRNA stability in breast cancer cells via 3'UTR-dependent processes." in: The Biochemical journal, Vol. 473, Issue 21, pp. 4027-4044, (2016) (PubMed).
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- Target
- ELAVL1 (ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 1 (Hu Antigen R) (ELAVL1))
- Alternative Name
- Elavl1,hur (ELAVL1 Products)
- Synonyms
- ELAV1 Protein, HUR Protein, Hua Protein, MelG Protein, HuR Protein, 2410055N02Rik Protein, W91709 Protein, elra Protein, fa25f08 Protein, fb59a02 Protein, fc60g02 Protein, hua Protein, wu:fa25f08 Protein, wu:fb59a02 Protein, wu:fc60g02 Protein, zHuA Protein, Elavl1 Protein, Xel-1 Protein, elav1 Protein, elrA Protein, hur Protein, melg Protein, p36 Protein, ElrA Protein, elavl1 Protein, elavl1-a Protein, elavl1-b Protein, ELAV like RNA binding protein 1 Protein, ELAV-like protein 1 Protein, ELAV (embryonic lethal, abnormal vision)-like 1 (Hu antigen R) Protein, ELAV like RNA binding protein 1a Protein, ELAV like RNA binding protein 1 L homeolog Protein, ELAV like RNA binding protein 1 S homeolog Protein, ELAVL1 Protein, Elavl1 Protein, elav1 Protein, elavl1a Protein, elavl1.L Protein, elavl1.S Protein
- Background
- The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3' untranslated regions of mRNAs. AREs signal degradation of mRNAs as a means to regulate gene expression, thus by binding AREs, the ELAVL family of proteins play a role in stabilizing ARE-containing mRNAs. This gene has been implicated in a variety of biological processes and has been linked to a number of diseases, including cancer. It is highly expressed in many cancers, and could be potentially useful in cancer diagnosis, prognosis, and therapy.
- Molecular Weight
- 35.9 kDa
- NCBI Accession
- NP_001410
- Pathways
- AMPK Signaling
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