Dysferlin Protein (DYSF) (Transcript Variant 1) (Myc-DYKDDDDK Tag)
DYSF
Origin: Human
Host: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
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- Target See all Dysferlin (DYSF) products
- Dysferlin (DYSF)
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 1
- Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Dysferlin protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Dysferlin (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- Dysferlin (DYSF)
- Alternative Name
- Dysferlin (DYSF Products)
- Synonyms
- DYSF Protein, fb73b05 Protein, wu:fb73b05 Protein, si:rp71-50c18.1 Protein, DKFZp459E1226 Protein, 2310004N10Rik Protein, AI604795 Protein, D6Pas3 Protein, mFLJ00175 Protein, FER1L1 Protein, LGMD2B Protein, MMD1 Protein, dysferlin Protein, dysferlin, limb girdle muscular dystrophy 2B (autosomal recessive) Protein, myoferlin Protein, DYSF Protein, dysf Protein, LOC589501 Protein, Dysf Protein
- Background
- The protein encoded by this gene belongs to the ferlin family and is a skeletal muscle protein found associated with the sarcolemma. It is involved in muscle contraction and contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. In addition, the protein encoded by this gene binds caveolin-3, a skeletal muscle membrane protein which is important in the formation of caveolae. Specific mutations in this gene have been shown to cause autosomal recessive limb girdle muscular dystrophy type 2B (LGMD2B) as well as Miyoshi myopathy. Alternative splicing results in multiple transcript variants.
- Molecular Weight
- 241.2 kDa
- NCBI Accession
- NP_001124459
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