DNM2 Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)
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- Target See all DNM2 Proteins
- DNM2 (Dynamin 2 (DNM2))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 3
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This DNM2 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Dynamin-2 (transcript variant 3) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product DNM2 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- DNM2 (Dynamin 2 (DNM2))
- Alternative Name
- Dynamin-2 (DNM2 Products)
- Synonyms
- dynamin-2 Protein, cmtdi1 Protein, cmtdib Protein, dyn2 Protein, dynII Protein, CMT2M Protein, CMTDI1 Protein, CMTDIB Protein, DI-CMTB Protein, DYN2 Protein, DYNII Protein, LCCS5 Protein, Dyn2 Protein, Udnm Protein, DYIIAAB Protein, dnm2 Protein, zgc:114072 Protein, dynamin 2 Protein, dynamin 2 L homeolog Protein, dynamin 2a Protein, dynamin 2-like Protein, DNM2 Protein, dnm2 Protein, dnm2.L Protein, Dnm2 Protein, dnm2a Protein, DNM2L Protein
- Background
- Dynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence similarity over the N-terminal portion of the molecule, which contains the GTPase domain. Dynamins are associated with microtubules. They have been implicated in cell processes such as endocytosis and cell motility, and in alterations of the membrane that accompany certain activities such as bone resorption by osteoclasts. Dynamins bind many proteins that bind actin and other cytoskeletal proteins. Dynamins can also self-assemble, a process that stimulates GTPase activity. Five alternatively spliced transcripts encoding different proteins have been described. Additional alternatively spliced transcripts may exist, but their full-length nature has not been determined.
- Molecular Weight
- 97.5 kDa
- NCBI Accession
- NP_004936
- Pathways
- Toll-Like Receptors Cascades
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