DCTN3 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- Target See all DCTN3 (Dctn3) Proteins
- DCTN3 (Dctn3) (Dynactin 3 (p22) (Dctn3))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 1
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This DCTN3 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Dynactin subunit 3 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product Dctn3 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- DCTN3 (Dctn3) (Dynactin 3 (p22) (Dctn3))
- Alternative Name
- Dynactin Subunit 3 (Dctn3 Products)
- Synonyms
- zgc:92471 Protein, wu:fc38g10 Protein, p24 Protein, NV12799 Protein, DCTN-22 Protein, DCTN22 Protein, dynactin 3 (p22) Protein, dynactin subunit 3 Protein, dynactin 3 Protein, dctn3 Protein, LOC658790 Protein, Dctn3 Protein, DCTN3 Protein
- Background
- This gene encodes the smallest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, cytokinesis, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like most other dynactin subunits, exists only as a part of the dynactin complex. It is primarily an alpha-helical protein with very little coiled coil, and binds directly to the largest subunit (p150) of dynactin. Alternative splicing results in multiple transcript variants.
- Molecular Weight
- 20.9 kDa
- NCBI Accession
- NP_009165
- Pathways
- M Phase
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