DPH1 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2719693

Product Details

Target: DPH1 (DPH1 Homolog (DPH1))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This DPH1 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human DPH1 / OVAC1 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: DPH1 (DPH1 Homolog (DPH1))

Alternative Name: Dph1,ovac1 (DPH1 Products)

Synonyms: DPH1 Protein, DPH1-OVCA2 Protein, dph1-ovca2 Protein, dph2l Protein, dph2l1 Protein, ovca1 Protein, DPH2L Protein, DPH2L1 Protein, OVCA1 Protein, zgc:110702 Protein, 2310011M22Rik Protein, 4930488F09Rik Protein, AW551873 Protein, Dph2l1 Protein, Ovca1 Protein, RGD1562694 Protein, diphthamide biosynthesis 1 Protein, diphthamide biosynthesis protein 1 Protein, diphthamide biosynthesis 1 L homeolog Protein, 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 Protein, DPH1 Protein, NCU08503 Protein, ATEG_01183 Protein, LELG_00973 Protein, HCAG_03806 Protein, AOR_1_728014 Protein, PTRG_05729 Protein, CTRG_01524 Protein, UREG_06411 Protein, BDBG_05574 Protein, MCYG_04396 Protein, PITG_12187 Protein, MGYG_02224 Protein, LOC100284663 Protein, dph1.L Protein, dph1 Protein, Dph1 Protein, dph-1 Protein

Background: The protein encoded by this gene is an enzyme involved in the biosynthesis of diphthamide, a modified histidine found only in elongation factor-2 (EEF2). Diphthamide residues in EEF2 are targeted for ADP-ribosylation by diphtheria toxin and Pseudomonas exotoxin A. Defects in this gene have been associated with both ovarian cancer and autosomal recessive intellectual disability with short stature, craniofacial, and ectodermal anomalies.

Molecular Weight: 48.6 kDa

NCBI Accession: NP_001374