DISC1 Protein (Transcript Variant L) (Myc-DYKDDDDK Tag)
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- Target See all DISC1 Proteins
- DISC1 (Disrupted in Schizophrenia 1 (DISC1))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant L
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This DISC1 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human DISC1 (transcript variant L) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product DISC1 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- DISC1 (Disrupted in Schizophrenia 1 (DISC1))
- Alternative Name
- Disc1 (DISC1 Products)
- Synonyms
- DISC1 Protein, C1orf136 Protein, SCZD9 Protein, disrupted in schizophrenia 1 Protein, disrupted in schizophrenia 1 protein Protein, disc1 Protein, DISC1 Protein, LOC100580606 Protein, Disc1 Protein
- Background
- This gene encodes a protein with multiple coiled coil motifs which is located in the nucleus, cytoplasm and mitochondria. The protein is involved in neurite outgrowth and cortical development through its interaction with other proteins. This gene is disrupted in a t(111)(q42.1q14.3) translocation which segregates with schizophrenia and related psychiatric disorders in a large Scottish family. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
- Molecular Weight
- 93.4 kDa
- NCBI Accession
- NP_061132
- Pathways
- Regulation of Cell Size
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