Desmocollin 2 Protein (DSC2) (Myc-DYKDDDDK Tag)
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- Target See all Desmocollin 2 (DSC2) Proteins
- Desmocollin 2 (DSC2)
- Protein Type
- Recombinant
- Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Desmocollin 2 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Desmocollin-2 (transcript variant Dsc2a) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product DSC2 Protein
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Desmocollin 2 (DSC2) (AA 1-847) protein (GST tag)
DSC2 Origin: Human Host: Wheat germ Recombinant WB, AA, AP, ELISA
Desmocollin 2 (DSC2) (AA 589-687) protein (GST tag)DSC2 Origin: Human Host: Wheat germ Recombinant WB, AA, AP, ELISA
Desmocollin 2 (DSC2) (AA 444-534) protein (GST tag)DSC2 Origin: Human Host: Wheat germ Recombinant WB, AA, AP, ELISA
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- Desmocollin 2 (DSC2)
- Alternative Name
- Desmocollin-2 (DSC2 Products)
- Synonyms
- ARVD11 Protein, CDHF2 Protein, DG2 Protein, DGII/III Protein, DSC3 Protein, AW228162 Protein, Dsc2a Protein, Dsc2b Protein, DSC2 Protein, desmocollin 2 Protein, DSC2 Protein, Dsc2 Protein
- Background
- This gene encodes a member of the desmocollin protein subfamily. Desmocollins, along with desmogleins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmocollin family members on chromosome 18. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11, and reduced protein expression has been described in several types of cancer. Alternative splicing results in multiple transcript variants.
- Molecular Weight
- 97 kDa
- NCBI Accession
- NP_077740
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