beta 2 Defensin Protein
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- Target See all beta 2 Defensin (BD-2) Proteins
- beta 2 Defensin (BD-2) (Defensin beta 2 (BD-2))
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Application
- Functional Studies (Func), Antibody Production (AbP), Standard (STD), Protein Interaction (PI)
- Specificity
- Optimal preservation of protein structure, post-translational modifications and functions.
- Characteristics
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- Recombinant human Defensin beta 2 protein expressed in E. coli.
- Produced with end-sequenced ORF clone
- Tested for bioactivity.
- Purity
- > 95 % as determined by SDS-PAGE and Coomassie blue staining
- Endotoxin Level
- Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).
- Biological Activity Comment
- Determined by its ability to chemoattract immature human dendritic cells using a concentration of 10.0-100.0 ng/ml.
- Top Product
- Discover our top product BD-2 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays
Protein-protein interaction
In vitro biochemical assays and cell-based functional assays - Restrictions
- For Research Use only
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- Buffer
- Lyophilized from a 0.2 μM filtered solution of 20 mM phosphate buffer,100 mM NaCl, pH 7.2
- Handling Advice
- Resuspend the protein in the desired concentration in proper buffer
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- beta 2 Defensin (BD-2) (Defensin beta 2 (BD-2))
- Alternative Name
- Defensin beta 2 (BD-2 Products)
- Synonyms
- BD-2 Protein, BD-4 Protein, DEFB-4 Protein, hBD-4 Protein, BD2 Protein, DEFB2 Protein, defensin beta 2 Protein, defensin beta 104B Protein, beta defensin 2 Protein, Defb2 Protein, DEFB104B Protein, SBD2 Protein
- Background
- Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 4, an antibiotic peptide which is locally regulated by inflammation.
- Molecular Weight
- 4.3 kDa
- NCBI Accession
- NP_004933
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