DEFA6 Protein (Myc-DYKDDDDK Tag)
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- Target See all DEFA6 Proteins
- DEFA6 (Defensin, alpha 6, Paneth Cell-Specific (DEFA6))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This DEFA6 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Defensin alpha 6 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product DEFA6 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- DEFA6 (Defensin, alpha 6, Paneth Cell-Specific (DEFA6))
- Alternative Name
- Defensin alpha 6 (DEFA6 Products)
- Synonyms
- DEFA6 Protein, DEF6 Protein, HD-6 Protein, Defcr6 Protein, defensin alpha 6 Protein, defensin, alpha 6, Paneth cell-specific Protein, defensin, alpha, 6 Protein, DEFA6 Protein, Defa6 Protein
- Background
- Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several alpha defensin genes appear to be clustered on chromosome 8. The protein encoded by this gene, defensin, alpha 6, is highly expressed in the secretory granules of Paneth cells of the small intestine, and likely plays a role in host defense of human bowel.
- Molecular Weight
- 8.9 kDa
- NCBI Accession
- NP_001917
- Pathways
- Cellular Response to Molecule of Bacterial Origin
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