EXO5 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2719347

Product Details

Target: EXO5 (Exonuclease 5 (EXO5))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This EXO5 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human Exonuclease V protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: EXO5 (Exonuclease 5 (EXO5))

Alternative Name: Defects in Morphology 1 Homolog (S. Cerevisiae) (Dem1) (EXO5 Products)

Synonyms: C1orf176 Protein, DEM1 Protein, Exo V Protein, hExo5 Protein, 3110037I16Rik Protein, AV297100 Protein, Dem1 Protein, mExo5 Protein, exonuclease 5 Protein, EXO5 Protein, Exo5 Protein

Background: The protein encoded by this gene is a single-stranded DNA (ssDNA)-specific exonuclease that can slide along the DNA before cutting it. However, human replication protein A binds ssDNA and restricts sliding of the encoded protein, providing a 5&apos-directionality to the enzyme. This protein localizes to nuclear repair loci after DNA damage.

Molecular Weight: 41.6 kDa

NCBI Accession: NP_073611