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BID Protein (Transcript Variant 2)

BID Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2715263
  • Target See all BID Proteins
    BID (BH3 Interacting Domain Death Agonist (BID))
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant 2
    Origin
    • 10
    • 4
    • 3
    • 1
    • 1
    Human
    Source
    • 10
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human BID (transcript variant 2) protein expressed in E. coli.
    • Produced with end-sequenced ORF clone
    Purity
    > 95 % as determined by SDS-PAGE and Coomassie blue staining
    Endotoxin Level
    < 0.1 EU per μg protein as determined by LAL test
    Top Product
    Discover our top product BID Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    20 mM Phosphate buffer, 100 mM KCl, pH 7.4. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    BID (BH3 Interacting Domain Death Agonist (BID))
    Alternative Name
    Bid (BID Products)
    Synonyms
    FP497 Protein, 2700049M22Rik Protein, AI875481 Protein, AU022477 Protein, BID Protein, bid Protein, si:ch211-238n5.6 Protein, fp497 Protein, xbid Protein, DKFZp469E066 Protein, BH3 interacting domain death agonist Protein, BH3 interacting domain death agonist S homeolog Protein, BID Protein, Bid Protein, bida Protein, bid.S Protein, bid Protein
    Background
    This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8) CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined.
    Molecular Weight
    22 kDa
    NCBI Accession
    NP_001187
    Pathways
    Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
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