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beta-2 Microglobulin Protein

This Recombinant beta-2 Microglobulin protein is expressed in HEK-293 Cells.
Catalog No. ABIN2715229

Quick Overview for beta-2 Microglobulin Protein (ABIN2715229)

Target

See all beta-2 Microglobulin (B2M) Proteins
beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))

Protein Type

Recombinant

Origin

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Human

Source

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HEK-293 Cells

Application

Antibody Production (AbP), Standard (STD)

Purity

> 95 % as determined by SDS-PAGE and Coomassie blue staining
  • Characteristics

    • Recombinant human Beta-2-microglobulin protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone

    Endotoxin Level

    < 0.1 EU per μg protein as determined by LAL test
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  • Application Notes

    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays

    Restrictions

    For Research Use only
  • Buffer

    Lyophilized from a 0.2 μM filtered solution of 20 mM Phosphate buffer, 150 mM NaCl, pH 7.2. Stable for at least 6 months from date of receipt under proper storage and handling conditions.

    Storage

    -80 °C

    Storage Comment

    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target

    beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))

    Alternative Name

    beta-2-Microglobulin

    Background

    This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. The encoded antimicrobial protein displays antibacterial activity in amniotic fluid. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.[provided by RefSeq, Aug 2014].

    Molecular Weight

    12.8 kDa

    NCBI Accession

    NP_004039

    Pathways

    TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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