BCKDHB Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- Target See all BCKDHB Proteins
- BCKDHB (Branched Chain Keto Acid Dehydrogenase E1, beta Polypeptide (BCKDHB))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 1
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This BCKDHB protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human BCKDHB (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product BCKDHB Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- BCKDHB (Branched Chain Keto Acid Dehydrogenase E1, beta Polypeptide (BCKDHB))
- Alternative Name
- Bckdhb (BCKDHB Products)
- Synonyms
- zgc:158777 Protein, BCKDHB Protein, E1B Protein, dJ279A18.1 Protein, branched chain keto acid dehydrogenase E1, beta polypeptide Protein, branched chain keto acid dehydrogenase E1 subunit beta Protein, branched chain keto acid dehydrogenase E1, beta polypeptide S homeolog Protein, branched chain ketoacid dehydrogenase E1, beta polypeptide Protein, BCKDHB Protein, bckdhb Protein, bckdhb.S Protein, Bckdhb Protein
- Background
- This gene encodes the E1 beta subunit of branched-chain keto acid dehydrogenase, which is a multienzyme complex associated with the inner membrane of mitochondria. This enzyme complex functions in the catabolism of branched-chain amino acids. Mutations in this gene have been associated with maple syrup urine disease (MSUD), type 1B, a disease characterized by a maple syrup odor to the urine in addition to mental and physical retardation and feeding problems. Alternative splicing at this locus results in multiple transcript variants.
- Molecular Weight
- 37.8 kDa
- NCBI Accession
- NP_898871
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