APOC3 Protein (Myc-DYKDDDDK Tag)
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- Target See all APOC3 Proteins
- APOC3 (Apolipoprotein C-III (APOC3))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This APOC3 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Apolipoprotein C III / ApoC3 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product APOC3 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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Static and turnover kinetic measurement of protein biomarkers involved in triglyceride metabolism including apoB48 and apoA5 by LC/MS/MS." in: Journal of lipid research, Vol. 55, Issue 6, pp. 1179-87, (2016) (PubMed).
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Static and turnover kinetic measurement of protein biomarkers involved in triglyceride metabolism including apoB48 and apoA5 by LC/MS/MS." in: Journal of lipid research, Vol. 55, Issue 6, pp. 1179-87, (2016) (PubMed).
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- Target
- APOC3 (Apolipoprotein C-III (APOC3))
- Alternative Name
- Apolipoprotein C III (Apo Ciii) (APOC3 Products)
- Synonyms
- APOC3 Protein, APOCIII Protein, HALP2 Protein, Apoc Protein, ApoC-III Protein, apo-CIII Protein, Apo-CIII Protein, apolipoprotein C3 Protein, apolipoprotein C-III Protein, APOC3 Protein, Apoc3 Protein
- Background
- Apolipoprotein C-III is a very low density lipoprotein (VLDL) protein. APOC3 inhibits lipoprotein lipase and hepatic lipase it is thought to delay catabolism of triglyceride-rich particles. The APOA1, APOC3 and APOA4 genes are closely linked in both rat and human genomes. The A-I and A-IV genes are transcribed from the same strand, while the A-1 and C-III genes are convergently transcribed. An increase in apoC-III levels induces the development of hypertriglyceridemia.
- Molecular Weight
- 8.7 kDa
- NCBI Accession
- NP_000031
- Pathways
- Carbohydrate Homeostasis, Lipid Metabolism
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