Ensa Protein (Transcript Variant 8) (Myc-DYKDDDDK Tag)
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- Target See all Ensa (ENSA) Proteins
- Ensa (ENSA) (Endosulfine alpha (ENSA))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 8
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Ensa protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Alpha-endosulfine / ENSA (transcript variant 8) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product ENSA Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- Ensa (ENSA) (Endosulfine alpha (ENSA))
- Alternative Name
- alpha-Endosulfine (Ensa) (ENSA Products)
- Synonyms
- ARPP-19e Protein, 1700020C18Rik Protein, 2610007F17Rik Protein, AI451924 Protein, ensa Protein, si:dkeyp-24a7.3 Protein, ensaa Protein, endosulfine alpha Protein, endosulfine alpha a Protein, endosulfine alpha S homeolog Protein, ENSA Protein, Ensa Protein, ensa Protein, ensaa Protein, ensa.S Protein
- Background
- The protein encoded by this gene belongs to a highly conserved cAMP-regulated phosphoprotein (ARPP) family. This protein was identified as an endogenous ligand for the sulfonylurea receptor, ABCC8/SUR1. ABCC8 is the regulatory subunit of the ATP-sensitive potassium (KATP) channel, which is located on the plasma membrane of pancreatic beta cells and plays a key role in the control of insulin release from pancreatic beta cells. This protein is thought to be an endogenous regulator of KATP channels. In vitro studies have demonstrated that this protein modulates insulin secretion through the interaction with KATP channel, and this gene has been proposed as a candidate gene for type 2 diabetes. At least eight alternatively spliced transcript variants encoding distinct isoforms have been observed.
- Molecular Weight
- 11.8 kDa
- NCBI Accession
- NP_997051
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