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A2ML1 Protein (Myc-DYKDDDDK Tag)

A2ML1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2714611
  • Target See all A2ML1 Proteins
    A2ML1 (alpha-2-Macroglobulin-Like 1 (A2ML1))
    Protein Type
    Recombinant
    Origin
    Human
    Source
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This A2ML1 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human Alpha-2-macroglobulin-like 1 (A2ML1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product A2ML1 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    A2ML1 (alpha-2-Macroglobulin-Like 1 (A2ML1))
    Abstract
    A2ML1 Products
    Synonyms
    CPAMD9 Protein, alpha-2-macroglobulin like 1 Protein, A2ML1 Protein
    Background
    This gene encodes a member of the alpha-macroglobulin superfamily. The encoded protein is thought to be an N-glycosylated monomeric protein that acts as an inhibitor of several proteases. It has been shown to form covalent interactions with proteases, and has been reported as the p170 antigen recognized by autoantibodies in the autoimmune disease paraneoplastic pemphigus (PNP PMID:20805888). Mutations in these gene have also been associated with some cases of Noonan syndrome (NS PMID:24939586) as well as some cases of otitis media (PMID:26121085). Alternative splicing results in multiple transcript variants encoding different isoforms.
    Molecular Weight
    161 kDa
    NCBI Accession
    NP_653271
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