A2ML1 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2714611

Product Details

Target: A2ML1 (alpha-2-Macroglobulin-Like 1 (A2ML1))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This A2ML1 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human Alpha-2-macroglobulin-like 1 (A2ML1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: A2ML1 (alpha-2-Macroglobulin-Like 1 (A2ML1))

Abstract: A2ML1 Products

Synonyms: CPAMD9 Protein, alpha-2-macroglobulin like 1 Protein, A2ML1 Protein

Background: This gene encodes a member of the alpha-macroglobulin superfamily. The encoded protein is thought to be an N-glycosylated monomeric protein that acts as an inhibitor of several proteases. It has been shown to form covalent interactions with proteases, and has been reported as the p170 antigen recognized by autoantibodies in the autoimmune disease paraneoplastic pemphigus (PNP PMID:20805888). Mutations in these gene have also been associated with some cases of Noonan syndrome (NS PMID:24939586) as well as some cases of otitis media (PMID:26121085). Alternative splicing results in multiple transcript variants encoding different isoforms.

Molecular Weight: 161 kDa

NCBI Accession: NP_653271