AKR1C2 Protein (Myc-DYKDDDDK Tag)
-
- Target See all AKR1C2 Proteins
- AKR1C2 (Aldo-keto Reductase Family 1, Member C2 (AKR1C2))
- Protein Type
- Recombinant
- Origin
- Human
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This AKR1C2 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
-
- Recombinant human AKR1C2 / DDH2 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product AKR1C2 Protein
-
-
- Application Notes
-
Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
-
The tag is located at the C-terminal.
- Restrictions
- For Research Use only
-
- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
-
- Target
- AKR1C2 (Aldo-keto Reductase Family 1, Member C2 (AKR1C2))
- Alternative Name
- Akr1c2,ddh2 (AKR1C2 Products)
- Synonyms
- AKR1C-pseudo Protein, BABP Protein, DD Protein, DD2 Protein, DDH2 Protein, HAKRD Protein, HBAB Protein, MCDR2 Protein, SRXY8 Protein, Akr1c21 Protein, aldo-keto reductase family 1 member C2 Protein, aldo-keto reductase family 1, member C2 Protein, AKR1C2 Protein, Akr1c2 Protein
- Background
- This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding two different isoforms have been found for this gene.
- Molecular Weight
- 36.6 kDa
- NCBI Accession
- NP_995317
- Pathways
- Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process
-