Smooth Muscle Actin Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- Target See all Smooth Muscle Actin (ACTA2) Proteins
- Smooth Muscle Actin (ACTA2) (Actin, alpha 2, Smooth Muscle, Aorta (ACTA2))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 1
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Smooth Muscle Actin protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human ACTA2 / aortic smooth muscle Actin (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product ACTA2 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- Smooth Muscle Actin (ACTA2) (Actin, alpha 2, Smooth Muscle, Aorta (ACTA2))
- Alternative Name
- Acta2,aortic Smooth Muscle Actin (ACTA2 Products)
- Synonyms
- AAT6 Protein, ACTSA Protein, MYMY5 Protein, GAMMA-ACTIN Protein, ACT Protein, ACTA3 Protein, ACTE Protein, ACTL3 Protein, ACTSG Protein, Act-4 Protein, Act4 Protein, SMGA Protein, 0610041G09Rik Protein, Actvs Protein, SMalphaA Protein, a-SMA Protein, alphaSMA Protein, wu:fb63d03 Protein, ASMA Protein, SMactin Protein, a-sma Protein, aat6 Protein, actsa Protein, mymy5 Protein, sm-actin Protein, ACTA2 Protein, actc1 Protein, ACT-4 Protein, asma Protein, ACTGE Protein, actin, alpha 2, smooth muscle, aorta Protein, actin, gamma 2, smooth muscle, enteric Protein, actin, alpha 2, smooth muscle, aorta L homeolog Protein, ACTA2 Protein, ACTG2 Protein, Actg2 Protein, Acta2 Protein, acta2 Protein, acta2.L Protein
- Background
- The protein encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Defects in this gene cause aortic aneurysm familial thoracic type 6. Multiple alternatively spliced variants, encoding the same protein, have been identified.
- Molecular Weight
- 41.8 kDa
- NCBI Accession
- NP_001135417
- Pathways
- Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development
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