ABHD12 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- Target See all ABHD12 Proteins
- ABHD12 (Abhydrolase Domain Containing 12 (ABHD12))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 1
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This ABHD12 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human ABHD12 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product ABHD12 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- ABHD12 (Abhydrolase Domain Containing 12 (ABHD12))
- Alternative Name
- Abhd12 (ABHD12 Products)
- Synonyms
- ABHD12 Protein, 1500011G07Rik Protein, 6330583M11Rik Protein, AI431047 Protein, AW547313 Protein, ABHD12A Protein, BEM46L2 Protein, C20orf22 Protein, PHARC Protein, dJ965G21.2 Protein, abhydrolase domain containing 12 Protein, abhydrolase domain containing 12 S homeolog Protein, ABHD12 Protein, CC1G_02966 Protein, PTRG_02160 Protein, abhd12.S Protein, Abhd12 Protein
- Background
- This gene encodes an enzyme that catalyzes the hydrolysis of 2-arachidonoyl glycerol (2-AG), the main endocannabinoid lipid transmitter that acts on cannabinoid receptors, CB1 and CB2. The endocannabinoid system is involved in a wide range of physiological processes, including neurotransmission, mood, appetite, pain appreciation, addiction behavior, and inflammation. Mutations in this gene are associated with the neurodegenerative disease, PHARC (polyneuropathy, hearing loss, ataxia, retinitis pigmentosa, and cataract), resulting from an inborn error of endocannabinoid metabolism. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jan 2011].
- Molecular Weight
- 44.9 kDa
- NCBI Accession
- NP_001035937
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