COA5 Protein (Myc-DYKDDDDK Tag)
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- Target See all COA5 Proteins
- COA5 (Cytochrome C Oxidase Assembly Factor 5 (COA5))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This COA5 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Chromosome 2 open reading frame 64 (C2orf64) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product COA5 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- COA5 (Cytochrome C Oxidase Assembly Factor 5 (COA5))
- Alternative Name
- Chromosome 2 Open Reading Frame 64 (c2orf64) (COA5 Products)
- Synonyms
- C2orf64 Protein, C11H2ORF64 Protein, 6330578E17Rik Protein, Pet191 Protein, 1700001A24Rik Protein, zgc:153408 Protein, c2orf64 Protein, pet191 Protein, chromosome 2 open reading frame 64 Protein, cytochrome c oxidase assembly factor 5 Protein, cytochrome C oxidase assembly factor 5 Protein, cytochrome c oxidase assembly factor 5 S homeolog Protein, COA5 Protein, Coa5 Protein, coa5 Protein, coa5.S Protein
- Background
- This gene encodes an ortholog of yeast Pet191, which in yeast is a subunit of a large oligomeric complex associated with the mitochondrial inner membrane, and required for the assembly of the cytochrome c oxidase complex. Mutations in this gene are associated with mitochondrial complex IV deficiency, a disorder of the mitochondrial respiratory chain with heterogeneous clinical manifestations, ranging from isolated myopathy to a severe disease affecting several tissues and organs.
- Molecular Weight
- 8.2 kDa
- NCBI Accession
- NP_001008216
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