Chitotriosidase 1 Protein (Myc-DYKDDDDK Tag)
CHIT1
Origin: Human
Host: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
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- Target See all Chitotriosidase 1 (CHIT1) Proteins
- Chitotriosidase 1 (CHIT1) (Chitotriosidase (CHIT1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Chitotriosidase 1 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Chitinase 1 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product CHIT1 Protein
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Chitotriosidase (CHIT1) (AA 1-466) protein (GST tag)
CHIT1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Chitotriosidase (CHIT1) (AA 60-169) protein (GST tag)CHIT1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- Chitotriosidase 1 (CHIT1) (Chitotriosidase (CHIT1))
- Alternative Name
- Chitinase 1 (CHIT1 Products)
- Synonyms
- CHI3 Protein, CHIT Protein, CHITD Protein, CHIT1 Protein, chio Protein, 2300002L19Rik Protein, chitinase 1 Protein, chitinase 1 (chitotriosidase) Protein, CHIT1 Protein, chit1 Protein, Chit1 Protein
- Background
- Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens. Several alternatively spliced transcript variants have been described for this gene.
- Molecular Weight
- 51.5 kDa
- NCBI Accession
- NP_003456
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