CERKL Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- Target See all CERKL Proteins
- CERKL (Ceramide Kinase-Like (CERKL))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 1
- Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CERKL protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human CERKL (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product CERKL Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- CERKL (Ceramide Kinase-Like (CERKL))
- Alternative Name
- Cerkl (CERKL Products)
- Synonyms
- RGD1561057 Protein, Gm1958 Protein, Rp26 Protein, GB19002 Protein, RP26 Protein, zgc:162213 Protein, ceramide kinase like Protein, ceramide kinase-like Protein, ceramide kinase Protein, CERKL Protein, Cerkl Protein, LOC408315 Protein, CERK Protein, LOC100566923 Protein, LOC100645684 Protein, cerkl Protein
- Background
- This gene was initially identified as a locus (RP26) associated with an autosomal recessive form of retinitis pigmentosa (arRP) disease. This gene encodes a protein with ceramide kinase-like domains, however, the protein does not phosphorylate ceramide and its target substrate is currently unknown. This protein may be a negative regulator of apoptosis in photoreceptor cells. Mutations in this gene cause a form of retinitis pigmentosa characterized by autosomal recessive cone and rod dystrophy (arCRD). Alternative splicing of this gene results in multiple transcript variants encoding different isoforms and non-coding transcripts.[provided by RefSeq, May 2010].
- Molecular Weight
- 59.4 kDa
- NCBI Accession
- NP_963842
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