ACTR1A Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2713914

Product Details

Target: ACTR1A (Alpha Centractin (ACTR1A))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This ACTR1A protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human Centractin alpha protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: ACTR1A (Alpha Centractin (ACTR1A))

Alternative Name: Centractin alpha (ACTR1A Products)

Synonyms: ARP1 Protein, CTRN1 Protein, Arp1 Protein, alpha-Arp1 Protein, arp1 Protein, centractin Protein, ctrn1 Protein, ACTR1A Protein, ARP1 actin related protein 1 homolog A Protein, ARP1 actin-related protein 1A, centractin alpha Protein, ARP1 actin-related protein 1 homolog A, centractin alpha Protein, ARP1 actin related protein 1 homolog A L homeolog Protein, alpha-centractin Protein, actin-2 Protein, ACTR1A Protein, Actr1a Protein, actr1a.L Protein, actr1a Protein, PTRG_02540 Protein, PAAG_06972 Protein, MCYG_01044 Protein, VDBG_00685 Protein, MGYG_00946 Protein, DICPUDRAFT_88548 Protein, PGTG_04034 Protein, Tsp_06409 Protein

Background: This gene encodes a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60 % identical at the amino acid level to conventional actin.

Molecular Weight: 42.4 kDa

NCBI Accession: NP_005727

Pathways: M Phase