ITGA6 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
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- Target See all ITGA6 Proteins
- ITGA6 (Integrin, alpha 6 (ITGA6))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 2
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This ITGA6 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human CD49f / ITGA6 (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product ITGA6 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- ITGA6 (Integrin, alpha 6 (ITGA6))
- Alternative Name
- Cd49f,itga6 (ITGA6 Products)
- Synonyms
- CD49f Protein, ITGA6B Protein, VLA-6 Protein, 5033401O05Rik Protein, AI115430 Protein, Cd49f Protein, ITGA6 Protein, inta6 Protein, im:6897425 Protein, itga6 Protein, si:dkey-32o22.1 Protein, wu:fb80g02 Protein, LOC100221694 Protein, si:dkey-18j14.1 Protein, wu:fl20e08 Protein, zgc:113088 Protein, integrin subunit alpha 6 Protein, integrin alpha 6 Protein, integrin subunit alpha 6 L homeolog Protein, integrin, alpha 6a Protein, integrin, alpha 6b Protein, ITGA6 Protein, Itga6 Protein, itga6.L Protein, itga6a Protein, itga6b Protein
- Background
- The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 6 subunit. This subunit may associate with a beta 1 or beta 4 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. The alpha 6 beta 4 integrin may promote tumorigenesis, while the alpha 6 beta 1 integrin may negatively regulate erbB2/HER2 signaling. Alternative splicing results in multiple transcript variants.
- Molecular Weight
- 117.2 kDa
- NCBI Accession
- NP_000201
- Pathways
- CXCR4-mediated Signaling Events, Brown Fat Cell Differentiation, Integrin Complex
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