Integrin Alpha2b Protein (CD41) (Myc-DYKDDDDK Tag)
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- Target See all Integrin Alpha2b (CD41) Proteins
- Integrin Alpha2b (CD41)
- Protein Type
- Recombinant
- Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Integrin Alpha2b protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human CD41 / ITGA2B protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product CD41 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- Integrin Alpha2b (CD41)
- Alternative Name
- Cd41,itga2b (CD41 Products)
- Synonyms
- AI172977 Protein, CD41 Protein, CD41B Protein, GpIIb Protein, alphaIIb Protein, BDPLT16 Protein, BDPLT2 Protein, GP2B Protein, GPIIb Protein, GT Protein, GTA Protein, HPA3 Protein, integrin alpha 2b Protein, integrin subunit alpha 2b Protein, Itga2b Protein, ITGA2B Protein
- Background
- This gene encodes a member of the integrin alpha chain family of proteins. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate through disulfide linkages to form a subunit of the alpha-IIb/beta-3 integrin cell adhesion receptor. This receptor plays a crucial role in the blood coagulation system, by mediating platelet aggregation. Mutations in this gene are associated with platelet-type bleeding disorders, which are characterized by a failure of platelet aggregation, including Glanzmann thrombasthenia.
- Molecular Weight
- 110 kDa
- NCBI Accession
- NP_000410
- Pathways
- Integrin Complex
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