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Integrin Alpha2b Protein (CD41) (Myc-DYKDDDDK Tag)

CD41 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2713707
  • Target See all Integrin Alpha2b (CD41) Proteins
    Integrin Alpha2b (CD41)
    Protein Type
    Recombinant
    Origin
    Human
    Source
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This Integrin Alpha2b protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human CD41 / ITGA2B protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product CD41 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    Integrin Alpha2b (CD41)
    Alternative Name
    Cd41,itga2b (CD41 Products)
    Synonyms
    AI172977 Protein, CD41 Protein, CD41B Protein, GpIIb Protein, alphaIIb Protein, BDPLT16 Protein, BDPLT2 Protein, GP2B Protein, GPIIb Protein, GT Protein, GTA Protein, HPA3 Protein, integrin alpha 2b Protein, integrin subunit alpha 2b Protein, Itga2b Protein, ITGA2B Protein
    Background
    This gene encodes a member of the integrin alpha chain family of proteins. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate through disulfide linkages to form a subunit of the alpha-IIb/beta-3 integrin cell adhesion receptor. This receptor plays a crucial role in the blood coagulation system, by mediating platelet aggregation. Mutations in this gene are associated with platelet-type bleeding disorders, which are characterized by a failure of platelet aggregation, including Glanzmann thrombasthenia.
    Molecular Weight
    110 kDa
    NCBI Accession
    NP_000410
    Pathways
    Integrin Complex
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