JAG1 Protein (Myc-DYKDDDDK Tag)
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- Target See all JAG1 Proteins
- JAG1 (Jagged 1 (JAG1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This JAG1 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human CD339 / JAG1 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product JAG1 Protein
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Jagged 1 (JAG1) (AA 531-620) protein (GST tag)
JAG1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Jagged 1 (JAG1) (AA 37-119) protein (GST tag)JAG1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Jagged 1 (JAG1) (AA 1-1067), (Extracellular Domain) (Active) protein (Fc Tag)JAG1 Origin: Human Host: HEK-293 Cells Recombinant >90 % (SDS-PAGE) SDS Active
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- JAG1 (Jagged 1 (JAG1))
- Alternative Name
- Cd339,jag1 (JAG1 Products)
- Synonyms
- AGS Protein, AHD Protein, AWS Protein, CD339 Protein, HJ1 Protein, JAGL1 Protein, ABE2 Protein, Gsfabe2 Protein, Htu Protein, Ozz Protein, Ser-1 Protein, JAG1 Protein, jag3 Protein, cb243 Protein, jag1 Protein, sb:cb243 Protein, serrateC Protein, jagged1 Protein, serrate Protein, serrate-1 Protein, x-serrate-1 Protein, jagged 1 Protein, jagged 1b Protein, jagged 1a Protein, jagged 1 L homeolog Protein, JAG1 Protein, Jag1 Protein, jag1 Protein, jag1b Protein, jag1a Protein, jag1.L Protein
- Background
- The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis.
- Molecular Weight
- 133.6 kDa
- NCBI Accession
- NP_000205
- Pathways
- Notch Signaling, Stem Cell Maintenance
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