CD2AP Protein (Myc-DYKDDDDK Tag)
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- Target See all CD2AP (Cd2ap) Proteins
- CD2AP (Cd2ap) (CD2-Associated Protein (Cd2ap))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CD2AP protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human CD2-associated protein protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product Cd2ap Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- CD2AP (Cd2ap) (CD2-Associated Protein (Cd2ap))
- Alternative Name
- CD2-Associated Protein (Cd2ap Products)
- Synonyms
- cd2apl Protein, fj51c01 Protein, im:7153970 Protein, si:ch211-207n9.1 Protein, wu:fj51c01 Protein, zgc:103705 Protein, DKFZp469E061 Protein, CMS Protein, AL024079 Protein, C78928 Protein, METS-1 Protein, Mets1 Protein, CD2-associated protein L homeolog Protein, CD2 associated protein Protein, CD2-associated protein Protein, cd2ap.L Protein, CD2AP Protein, cd2ap Protein, Cd2ap Protein
- Background
- This gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytosis and cytokinesis. Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease.
- Molecular Weight
- 71.3 kDa
- NCBI Accession
- NP_036252
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