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CD177 Protein (Myc-DYKDDDDK Tag)

CD177 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2713472
  • Target See all CD177 Proteins
    CD177 (CD177 Molecule (CD177))
    Protein Type
    Recombinant
    Origin
    • 8
    • 2
    Human
    Source
    • 4
    • 3
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This CD177 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human CD177 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product CD177 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    CD177 (CD177 Molecule (CD177))
    Alternative Name
    CD177 (CD177 Products)
    Synonyms
    HNA-2a Protein, HNA2A Protein, NB1 Protein, NB1 GP Protein, PRV-1 Protein, PRV1 Protein, RGD1562941 Protein, CD177 Protein, MGC157159 Protein, 1190003K14Rik Protein, Pdp3 Protein, CD177 molecule Protein, CD177 antigen Protein, CD177 Protein, Cd177 Protein
    Background
    This gene encodes a glycosyl-phosphatidylinositol (GPI)-linked cell surface glycoprotein that plays a role in neutrophil activation. The protein can bind platelet endothelial cell adhesion molecule-1 and function in neutrophil transmigration. Mutations in this gene are associated with myeloproliferative diseases. Over-expression of this gene has been found in patients with polycythemia rubra vera. Autoantibodies against the protein may result in pulmonary transfusion reactions, and it may be involved in Wegener&aposs granulomatosis. A related pseudogene, which is adjacent to this gene on chromosome 19, has been identified.
    Molecular Weight
    46.2 kDa
    NCBI Accession
    NP_065139
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