CD177 Protein (Myc-DYKDDDDK Tag)
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- Target See all CD177 Proteins
- CD177 (CD177 Molecule (CD177))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CD177 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human CD177 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product CD177 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- CD177 (CD177 Molecule (CD177))
- Alternative Name
- CD177 (CD177 Products)
- Synonyms
- HNA-2a Protein, HNA2A Protein, NB1 Protein, NB1 GP Protein, PRV-1 Protein, PRV1 Protein, RGD1562941 Protein, CD177 Protein, MGC157159 Protein, 1190003K14Rik Protein, Pdp3 Protein, CD177 molecule Protein, CD177 antigen Protein, CD177 Protein, Cd177 Protein
- Background
- This gene encodes a glycosyl-phosphatidylinositol (GPI)-linked cell surface glycoprotein that plays a role in neutrophil activation. The protein can bind platelet endothelial cell adhesion molecule-1 and function in neutrophil transmigration. Mutations in this gene are associated with myeloproliferative diseases. Over-expression of this gene has been found in patients with polycythemia rubra vera. Autoantibodies against the protein may result in pulmonary transfusion reactions, and it may be involved in Wegener&aposs granulomatosis. A related pseudogene, which is adjacent to this gene on chromosome 19, has been identified.
- Molecular Weight
- 46.2 kDa
- NCBI Accession
- NP_065139
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