MST1R Protein (DYKDDDDK-His Tag)

Catalog No. ABIN2713409

Product Details

Target: MST1R (Macrophage Stimulating 1 Receptor (C-Met-Related tyrosine Kinase) (MST1R))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This MST1R protein is labelled with DYKDDDDK-His Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human CD136 / MST1R (C-term DDK/His tag, transcript variant 1) protein expressed in Human 293HEK cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 1 x PBS, pH 7.4, 10 % glycerol. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: MST1R (Macrophage Stimulating 1 Receptor (C-Met-Related tyrosine Kinase) (MST1R))

Alternative Name: Cd136,mst1r (MST1R Products)

Synonyms: CD136 Protein, CDw136 Protein, PTK8 Protein, RON Protein, Fv-2 Protein, Fv2 Protein, Ron Protein, STK Protein, Cdw136 Protein, Ptk8 Protein, Stk Protein, macrophage stimulating 1 receptor Protein, macrophage stimulating 1 receptor (c-met-related tyrosine kinase) Protein, MST1R Protein, Mst1r Protein

Background: This gene encodes a cell surface receptor for macrophage-stimulating protein (MSP) with tyrosine kinase activity. The mature form of this protein is a heterodimer of disulfide-linked alpha and beta subunits, generated by proteolytic cleavage of a single-chain precursor. The beta subunit undergoes tyrosine phosphorylation upon stimulation by MSP. This protein is expressed on the ciliated epithelia of the mucociliary transport apparatus of the lung, and together with MSP, thought to be involved in host defense. Alternative splicing generates multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing.

Molecular Weight: 102 kDa

NCBI Accession: NP_002438

Pathways: RTK Signaling