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CBS Protein (Myc-DYKDDDDK Tag)

CBS Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2713257
  • Target See all CBS Proteins
    CBS (Cystathionine-beta-Synthase (CBS))
    Protein Type
    Recombinant
    Origin
    • 4
    • 2
    • 2
    • 1
    Human
    Source
    • 4
    • 3
    • 2
    HEK-293 Cells
    Purification tag / Conjugate
    This CBS protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human CBS protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product CBS Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    CBS (Cystathionine-beta-Synthase (CBS))
    Alternative Name
    Cbs (CBS Products)
    Synonyms
    hip4 Protein, GB12529 Protein, CBS Protein, DDBDRAFT_0189727 Protein, DDBDRAFT_0191292 Protein, DDB_0189727 Protein, DDB_0191292 Protein, cbs Protein, AI047524 Protein, AI303044 Protein, HIP4 Protein, cb442 Protein, wu:fb37g05 Protein, wu:fm61c07 Protein, wu:fq06c06 Protein, zgc:113704 Protein, cystathionine-beta-synthase L homeolog Protein, cystathionine-beta-synthase Protein, cystathionine beta-synthase Protein, cystathionine beta-synthase CBS Protein, cystathionine beta synthase Protein, cystathionine-beta-synthase S homeolog Protein, cystathionine-beta-synthase b Protein, cbs.L Protein, cbs Protein, Cbs Protein, CBS Protein, CNA06170 Protein, Tb11.02.5400 Protein, cysB Protein, LOC100635325 Protein, cbs.S Protein, cbsb Protein
    Background
    The protein encoded by this gene acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. The encoded protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria. This gene is a major contributor to cellular hydrogen sulfide production. Multiple alternatively spliced transcript variants have been found for this gene.
    Molecular Weight
    60.4 kDa
    NCBI Accession
    NP_000062
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