CBS Protein (Myc-DYKDDDDK Tag)
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- Target See all CBS Proteins
- CBS (Cystathionine-beta-Synthase (CBS))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CBS protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human CBS protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product CBS Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- CBS (Cystathionine-beta-Synthase (CBS))
- Alternative Name
- Cbs (CBS Products)
- Synonyms
- hip4 Protein, GB12529 Protein, CBS Protein, DDBDRAFT_0189727 Protein, DDBDRAFT_0191292 Protein, DDB_0189727 Protein, DDB_0191292 Protein, cbs Protein, AI047524 Protein, AI303044 Protein, HIP4 Protein, cb442 Protein, wu:fb37g05 Protein, wu:fm61c07 Protein, wu:fq06c06 Protein, zgc:113704 Protein, cystathionine-beta-synthase L homeolog Protein, cystathionine-beta-synthase Protein, cystathionine beta-synthase Protein, cystathionine beta-synthase CBS Protein, cystathionine beta synthase Protein, cystathionine-beta-synthase S homeolog Protein, cystathionine-beta-synthase b Protein, cbs.L Protein, cbs Protein, Cbs Protein, CBS Protein, CNA06170 Protein, Tb11.02.5400 Protein, cysB Protein, LOC100635325 Protein, cbs.S Protein, cbsb Protein
- Background
- The protein encoded by this gene acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. The encoded protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria. This gene is a major contributor to cellular hydrogen sulfide production. Multiple alternatively spliced transcript variants have been found for this gene.
- Molecular Weight
- 60.4 kDa
- NCBI Accession
- NP_000062
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