CASQ2 Protein (Myc-DYKDDDDK Tag)
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- Target See all CASQ2 Proteins
- CASQ2 (Calsequestrin 2 (CASQ2))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CASQ2 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Calsequestrin-2 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product CASQ2 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- CASQ2 (Calsequestrin 2 (CASQ2))
- Alternative Name
- Calsequestrin-2 (CASQ2 Products)
- Synonyms
- CASQ2 Protein, DKFZp468D075 Protein, AA033488 Protein, AW146219 Protein, ESTM52 Protein, cCSQ Protein, PDIB2 Protein, cardCSQ Protein, CASQ1 Protein, CAL Protein, calsequestrin 2 Protein, CASQ2 Protein, Casq2 Protein
- Background
- The protein encoded by this gene specifies the cardiac muscle family member of the calsequestrin family. Calsequestrin is localized to the sarcoplasmic reticulum in cardiac and slow skeletal muscle cells. The protein is a calcium binding protein that stores calcium for muscle function. Mutations in this gene cause stress-induced polymorphic ventricular tachycardia, also referred to as catecholaminergic polymorphic ventricular tachycardia 2 (CPVT2), a disease characterized by bidirectional ventricular tachycardia that may lead to cardiac arrest.
- Molecular Weight
- 44.2 kDa
- NCBI Accession
- NP_001223
- Pathways
- Negative Regulation of Transporter Activity
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