Calnexin Protein (CANX) (Transcript Variant 2) (His tag)
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- Target See all Calnexin (CANX) Proteins
- Calnexin (CANX)
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 2
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Calnexin protein is labelled with His tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Calnexin (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 95 % as determined by SDS-PAGE and Coomassie blue staining
- Endotoxin Level
- < 0.1 EU per μg protein as determined by LAL test
- Top Product
- Discover our top product CANX Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the N-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 20 mM Tris-HCl, 150 mM NaCl, 2 mM CaCl, 10 % Glycerol, pH 7.5. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- Calnexin (CANX)
- Alternative Name
- Calnexin (CANX Products)
- Synonyms
- CNX Protein, IP90 Protein, P90 Protein, 1110069N15Rik Protein, AI988026 Protein, Cnx Protein, D11Ertd153e Protein, canx Protein, clgn Protein, clnx Protein, cnx Protein, PP90 Protein, zgc:63524 Protein, wu:fe06b12 Protein, CANX Protein, calnexin Protein, CalNeXin Protein, calnexin L homeolog Protein, CANX Protein, Canx Protein, cnx-1 Protein, canx.L Protein, canx Protein, LOC100283947 Protein
- Background
- This gene encodes a member of the calnexin family of molecular chaperones. The encoded protein is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Alternatively spliced transcript variants encoding the same protein have been described.
- Molecular Weight
- 53.5 kDa
- NCBI Accession
- NP_001019820
- Pathways
- MAPK Signaling, Thyroid Hormone Synthesis
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