CACNB4 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
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- Target See all CACNB4 Proteins
- CACNB4 (Calcium Channel, Voltage-Dependent, beta 4 Subunit (CACNB4))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 2
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CACNB4 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human CACNB4 (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product CACNB4 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- CACNB4 (Calcium Channel, Voltage-Dependent, beta 4 Subunit (CACNB4))
- Alternative Name
- Cacnb4 (CACNB4 Products)
- Synonyms
- CAB4 Protein, CACNLB4 Protein, EA5 Protein, EIG9 Protein, EJM Protein, EJM4 Protein, EJM6 Protein, 3110038O15Rik Protein, Cchb4 Protein, lethargic Protein, lh Protein, CACNB4 Protein, cacnb4.2 Protein, calcium voltage-gated channel auxiliary subunit beta 4 Protein, calcium channel, voltage-dependent, beta 4 subunit Protein, calcium channel, voltage-dependent, beta 4a subunit Protein, CACNB4 Protein, Cacnb4 Protein, cacnb4.1 Protein, cacnb4 Protein, cacnb4a Protein
- Background
- This gene encodes a member of the beta subunit family of voltage-dependent calcium channel complex proteins. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. The protein encoded by this locus plays an important role in calcium channel function by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Certain mutations in this gene have been associated with idiopathic generalized epilepsy (IGE), juvenile myoclonic epilepsy (JME), and episodic ataxia, type 5.
- Molecular Weight
- 58 kDa
- NCBI Accession
- NP_000717
- Pathways
- cAMP Metabolic Process, Skeletal Muscle Fiber Development
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