Cofilin Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2712944

Product Details

Target: Cofilin (CFL1) (Cofilin 1 (CFL1))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This Cofilin protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human Cofilin-1 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: Cofilin (CFL1) (Cofilin 1 (CFL1))

Alternative Name: Cofilin-1 (CFL1 Products)

Synonyms: cfl1 Protein, xac1 Protein, xac2 Protein, cfl Protein, cb86 Protein, sb:cb86 Protein, zgc:56501 Protein, wu:fb18a04 Protein, wu:fk77b03 Protein, 12/8 Protein, ADF Protein, ADF/cofilin Protein, Adf Protein, CG4254 Protein, Cadf Protein, D-cof Protein, D61 Protein, Dmel\\CG4254 Protein, T8 Protein, Tsr Protein, cofilin Protein, cofilin/ADF Protein, cofilin/actin depolymerizing factor homolog Protein, l(2)03101 Protein, l(2)k03101 Protein, l(2)k05633 Protein, l(2)k13409 Protein, ntf Protein, CFL Protein, AA959946 Protein, Cof Protein, CFL1 Protein, cofilin 1 (non-muscle) L homeolog Protein, cofilin 1 (non-muscle) Protein, cofilin 1 (non-muscle), like Protein, cofilin 1 Protein, twinstar Protein, cofilin Protein, cofilin 1, non-muscle Protein, Contrafreeloading Protein, cfl1.L Protein, cfl1 Protein, cfl1l Protein, CFL1 Protein, tsr Protein, COF1 Protein, TSTA_042790 Protein, Cfl1 Protein, CFL Protein

Background: The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH -dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH -dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.[supplied by OMIM, Apr 2004]

Molecular Weight: 18.3 kDa

NCBI Accession: NP_005498

Pathways: Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus, CXCR4-mediated Signaling Events