CMBL Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2712894

Product Details

Target: CMBL (Carboxymethylenebutenolidase Homolog (CMBL))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This CMBL protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human CMBL protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: CMBL (Carboxymethylenebutenolidase Homolog (CMBL))

Alternative Name: Cmbl (CMBL Products)

Synonyms: JS-1 Protein, RGD1306952 Protein, 2310016A09Rik Protein, carboxymethylenebutenolidase homolog Protein, carboxymethylenebutenolidase-like (Pseudomonas) Protein, CMBL Protein, Cmbl Protein

Background: CMBL (EC 3.1.1.45) is a cysteine hydrolase of the dienelactone hydrolase family that is highly expressed in liver cytosol. CMBL preferentially cleaves cyclic esters, and it activates medoxomil-ester prodrugs in which the medoxomil moiety is linked to an oxygen atom (Ishizuka et al., 2010 [PubMed 20177059]).[supplied by OMIM, Apr 2010].

Molecular Weight: 27.9 kDa

NCBI Accession: NP_620164