Coronin 7 Protein (CORO7) (Myc-DYKDDDDK Tag)
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- Target See all Coronin 7 (CORO7) Proteins
- Coronin 7 (CORO7)
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Coronin 7 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Coronin-7 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product CORO7 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- Coronin 7 (CORO7)
- Abstract
- CORO7 Products
- Synonyms
- coronin-7 Protein, zgc:112352 Protein, MGC99303 Protein, Coronin-7 Protein, DKFZp459E084 Protein, 0610011B16Rik Protein, CRN7 Protein, POD1 Protein, AW048373 Protein, AW556392 Protein, Crn7 Protein, coronin 7 Protein, coronin 7 S homeolog Protein, coronin-7 Protein, CORO7 Protein, coro7 Protein, coro7.S Protein, LOC100477739 Protein, Coro7 Protein
- Background
- This gene encodes a member of the coronin protein family. However, unlike other coronin proteins, it is not an actin-binding protein but rather functions as an F-actin regulator directing anterograde Golgi to endosome transport. The encoded protein has two tandem WD-40 domain repeats and localizes to the trans-Golgi network. The protein undergoes K33-linked polyubiquitination via an E3 ligase complex. It is thought to play an essential role in maintenance of Golgi apparatus morphology. Alternative splicing results in multiple transcripts variants some of which form read-through transcripts with a neighboring gene.
- Molecular Weight
- 100.4 kDa
- NCBI Accession
- NP_078811
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