COQ3 Protein (Myc-DYKDDDDK Tag)
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- Target See all COQ3 Proteins
- COQ3 (Coenzyme Q3, Methyltransferase (COQ3))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This COQ3 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human COQ3 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product COQ3 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- COQ3 (Coenzyme Q3, Methyltransferase (COQ3))
- Alternative Name
- Coq3 (COQ3 Products)
- Synonyms
- 4732433J24 Protein, C77934 Protein, DHHBMT Protein, DHHBMTASE Protein, UG0215E05 Protein, bA9819.1 Protein, ATCOQ3 Protein, EMB3002 Protein, F7F1.13 Protein, F7F1_13 Protein, coenzyme Q 3 Protein, embryo defective 3002 Protein, coenzyme Q3 methyltransferase Protein, coenzyme Q3, methyltransferase Protein, coenzyme Q 3 Protein, Coq3 Protein, COQ3 Protein
- Background
- Ubiquinone, also known as coenzyme Q, or Q, is a critical component of the electron transport pathways of both eukaryotes and prokaryotes (Jonassen and Clarke, 2000 [PubMed 10777520]). This lipid consists of a hydrophobic isoprenoid tail and a quinone head group. The tail varies in length depending on the organism, but its purpose is to anchor coenzyme Q to the membrane. The quinone head group is responsible for the activity of coenzyme Q in the respiratory chain. The S. cerevisiae COQ3 gene encodes an O-methyltransferase required for 2 steps in the biosynthetic pathway of coenzyme Q. This enzyme methylates an early coenzyme Q intermediate, 3,4-dihydroxy-5-polyprenylbenzoic acid, as well as the final intermediate in the pathway, converting demethyl-ubiquinone to coenzyme Q. The COQ3 gene product is also capable of methylating the distinct prokaryotic early intermediate 2-hydroxy-6-polyprenyl phenol.[supplied by OMIM, Mar 2008].
- Molecular Weight
- 40.9 kDa
- NCBI Accession
- NP_059117
- Pathways
- Methionine Biosynthetic Process
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