PKC epsilon Protein (Myc-DYKDDDDK Tag)
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- Target See all PKC epsilon (PRKCE) Proteins
- PKC epsilon (PRKCE) (Protein Kinase C, epsilon (PRKCE))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This PKC epsilon protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human PRKCE protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product PRKCE Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- PKC epsilon (PRKCE) (Protein Kinase C, epsilon (PRKCE))
- Alternative Name
- Prkce (PRKCE Products)
- Synonyms
- PKCE Protein, nPKC-epsilon Protein, 5830406C15Rik Protein, PKC[e] Protein, PKCepsilon Protein, Pkce Protein, R75156 Protein, fj59b07 Protein, prkce Protein, wu:fj59b07 Protein, pkce Protein, pkc-epsilon Protein, PRKCH Protein, protein kinase C epsilon Protein, protein kinase C, epsilon Protein, protein kinase C, epsilon a Protein, PRKCE Protein, Prkce Protein, prkcea Protein, prkce Protein
- Background
- Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been shown to be involved in many different cellular functions, such as neuron channel activation, apoptosis, cardioprotection from ischemia, heat shock response, as well as insulin exocytosis. Knockout studies in mice suggest that this kinase is important for lipopolysaccharide (LPS)-mediated signaling in activated macrophages and may also play a role in controlling anxiety-like behavior.
- Molecular Weight
- 83.5 kDa
- NCBI Accession
- NP_005391
- Pathways
- TCR Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Myometrial Relaxation and Contraction, Regulation of Carbohydrate Metabolic Process, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling
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