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CD58 Protein (CD58) (His tag)

CD58 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. WB Active
Catalog No. ABIN2566429
  • Target See all CD58 Proteins
    CD58
    Protein Type
    Recombinant
    Biological Activity
    Active
    Origin
    Human
    Source
    • 7
    • 3
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This CD58 protein is labelled with His tag.
    Application
    Western Blotting (WB)
    Characteristics

    Measured in a cell proliferation assay using human CD3+ T cells in the presence of anti-CD3. The ED50 for this effect is typically 1 - 5 μg/mL in the presence of anti-CD3 immobilized at 25 ng/mL.

    Purity
    >95 % as determined by SDS-PAGE.
    Top Product
    Discover our top product CD58 Protein
  • Application Notes
    This recombinant protein can be used for WB. For research use only.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4
    Storage
    -80 °C,-20 °C
    Storage Comment
    Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
  • Target
    CD58
    Alternative Name
    CD58 (CD58 Products)
    Synonyms
    LFA-3 Protein, LFA3 Protein, ag3 Protein, CD58 molecule Protein, CD58 Protein
    Background
    CD antigen CD58 is also known as Lymphocyte function-associated antigen 3 (LFA-3). CD58 is a cell adhesion molecule expressed on Antigen Presenting Cells (APC), particularly macrophages. CD58 /LFA3 is ligand of the T-lymphocyte CD2 glycoprotein, which binds to CD2 (LFA-2) [3] on T cells and is important in strengthening the adhesion between the T cells and Professional Antigen Presenting Cells. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells. Polymorphisms in the CD58 gene are associated with increased risk for multiple sclerosis.
    Molecular Weight
    22.3 kDa
    Gene ID
    965
    UniProt
    P19256
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