RETNLG Protein
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- Target See all RETNLG products
- RETNLG (Resistin Like gamma (RETNLG))
- Protein Type
- Recombinant
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Origin
- Mouse
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Source
- Escherichia coli (E. coli)
- Sequence
- EGTLESIVEK KVKELLANRD DCPSTVTKTF SCTSITASGR LASCPSGMTV TGCACGYGCG SWDIRDGNTC HCQCSTMDWA TARCCQLA
- Purity
- < 98 % by SDS-PAGE gel and HPLC analyses.
- Endotoxin Level
- Endotoxin level is less than 0.1 ng per μg (1 EU/μg).
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Handling Advice
- As with any protein, exposing RELM gamma recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
- Storage
- -20 °C
- Storage Comment
- The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted RELM gamma is stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.
- Expiry Date
- 24 months
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- Target
- RETNLG (Resistin Like gamma (RETNLG))
- Alternative Name
- RELM gamma (RETNLG Products)
- Synonyms
- Fizz3 Protein, Relmg Protein, Xcp1 Protein, resistin like gamma Protein, Retnlg Protein
- Background
- RELMα belongs to a unique family of tissue-specific cytokines termed FIZZ (found in inflammatory zone) and RELM. The other three known members of this family , Resistin, RELMα and RELMbeta, are 85-94 amino acid secreted proteins sharing a conserved C-terminal domain characterized by 10 cysteine residues with a unique spacing motif of C-X11-C-X8-C-X-C-X3-C-X10-C-X-C-X-C-X9-C-C. RELM? is most closely related to RELMα but is distinctly secreted to bone marrow, spleen, lung, and in peripheral blood granulocytes. The physiological role of RELMγ , may include the promotion or regulation of promyelocytic differentiation, although the specific molecular targets of RELMγ , have not been identified. Recombinant murine RELMγ , is a 9.2 kDa monomeric protein containing 88 amino acid residues.
- Gene ID
- 245195
- NCBI Accession
- NP_853627
- OMIM
- 225007619
- UniProt
- Q7TM98
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