IL-3 beta Protein
IL-3 beta
Origin: Rat
Host: Escherichia coli (E. coli)
Recombinant
< 98 % by SDS-PAGE gel and HPLC analyses.
Active
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- Target See all IL-3 beta products
- IL-3 beta (Interleukin 3 beta (IL-3 beta))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Origin
- Rat
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Source
- Escherichia coli (E. coli)
- Sequence
- MISDRGSDAH HLLRTLDCRT IALEILVKLP YPQVSGLNNS DDKANLRNST LRRVNLDEFL KSQEEFDSQD TTDIKSKLQK LKCCIPAAAS DSVLPGVYNK DLDDFKKKLR FYVIHLKDLQ PVSVSRPPQP TSSSDNFRPM TVEC
- Characteristics
- The ED50 was determined by the dose - dependent stimulation of the proliferation of thymidine uptake by murine MC - 9 cells is < 10 ng/mL, corresponding to a specific activity of >1.0 x 105 units/mg.
- Purity
- < 98 % by SDS-PAGE gel and HPLC analyses.
- Endotoxin Level
- Endotoxin level is less than 0.1 ng per μg (1 EU/μg).
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Handling Advice
- As with any protein, exposing IL-3 beta recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
- Storage
- -20 °C
- Storage Comment
- The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted IL-3 beta is stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.
- Expiry Date
- 24 months
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- Target
- IL-3 beta (Interleukin 3 beta (IL-3 beta))
- Alternative Name
- IL-3 beta (IL-3 beta Products)
- Background
- IL-3 is a hematopoietic growth factor that promotes the survival, differentiation and proliferation of committed progenitor cells of the megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil and mast cell lineages. Produced by T cells, mast cells and eosinophils, IL-3 enhances thrombopoieses, phagocytosis, and antibody-mediated cellular cytotoxicity. Its ability to activate monocytes suggests that IL-3 may have additional immunoregulatory roles. Many of the IL-3 activities depend upon co-stimulation with other cytokines. IL-3 is species-specific, variably glycosylated cytokine. Recombinant rat IL-3beta is a 16.3 kDa globular protein containing 144 amino acid residues.
- Gene ID
- 171081
- NCBI Accession
- NP_598239
- OMIM
- 19424232
- UniProt
- Q78ZF5
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