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IL-24 Protein

IL24 Origin: Human Host: CHO Cells Recombinant < 95 % by SDS-PAGE gel and HPLC analyses.
Catalog No. ABIN2468661
  • Target See all IL-24 (IL24) Proteins
    IL-24 (IL24) (Interleukin 24 (IL24))
    Protein Type
    Recombinant
    Origin
    • 10
    • 3
    • 2
    Human
    Source
    • 6
    • 3
    • 3
    • 2
    • 1
    CHO Cells
    Sequence
    QEFHFGPCQV KGVVPQKLWE AFWAVKDTMQ AQDNITSARL LQQEVLQNVS DAESCYLVHT LLEFYLKTVF KNYHNRTVEV RTLKSFSTLA NNFVLIVSQL QPSQENEMFS IRDSAHRRFL LFRRAFKQLD VEAALTKALG EVDILLTWMQ KFYKLHHHHH H
    Purity
    < 95 % by SDS-PAGE gel and HPLC analyses.
    Top Product
    Discover our top product IL24 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Handling Advice
    As with any protein, exposing IL-24 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
    Storage
    -20 °C
    Storage Comment
    The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted IL-24 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.
    Expiry Date
    24 months
  • Target
    IL-24 (IL24) (Interleukin 24 (IL24))
    Alternative Name
    IL-24 (IL24 Products)
    Synonyms
    C49A Protein, FISP Protein, IL10B Protein, MDA7 Protein, MOB5 Protein, ST16 Protein, Mda7 Protein, St16 Protein, Mda-7 Protein, IL24 Protein, interleukin 24 Protein, IL24 Protein, Il24 Protein
    Background
    IL-24 is a secreted glycoprotein belonging to the IL-10 structural family of cytokines. It is produced by a variety of cell types, including B cells, CD4+ cells, NK cells, lymph node DCs, monocytes, and melanoma cells. IL-24 can signal through the IL20R1/IL20R2 and IL22R1/IL20R2 receptors to initiate a signaling cascade which includes the induction of JAK1/STAT3 phosphorylation. IL-24 is, functionally, a pleiotropic protein but is generally characterized as an anti-cancer cytokine that can selectively inhibit growth of a wide variety of human cancer cells through activities that include the induction of differentiation and apoptosis, and the suppression of angiogenesis and cell proliferation. Recombinant human IL-24 is an 18.9 kDa glycoprotein, containing 161 amino acid residues, including a C-terminal His-tag.
    Gene ID
    11009
    NCBI Accession
    NP_001172085
    OMIM
    297632401
    UniProt
    Q13007
    Pathways
    Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Autophagy
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