GDF7 Protein
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- Target See all GDF7 Proteins
- GDF7 (Growth Differentiation Factor 7 (GDF7))
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Sequence
- TALAGTRTAQ GSGGGAGRGH GRRGRSRCSR KPLHVDFKEL GWDDWIIAPL DYEAYHCEGL CDFPLRSHLE PTNHAIIQTL LNSMAPDAAP ASCCVPARLS PISILYIDAA NNVVYKQYED MVVEACGCR
- Characteristics
- Biological activity was determined by its ability to inhibit induced alkaline phosphatase production by ATDC-5 chondrogenic cells.
- Purity
- < 98 % by SDS-PAGE gel and HPLC analyses.
- Top Product
- Discover our top product GDF7 Protein
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Growth Differentiation Factor 7 (GDF7) (AA 361-450) protein (GST tag)
GDF7 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Growth Differentiation Factor 7 (GDF7) (AA 204-301) protein (GST tag)GDF7 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Growth Differentiation Factor 7 (GDF7) proteinGDF7 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, ELISA, IP
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Handling Advice
- As with any protein, exposing GDF-7 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
- Storage
- -20 °C
- Storage Comment
- The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted GDF-7 stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.
- Expiry Date
- 24 months
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- Target
- GDF7 (Growth Differentiation Factor 7 (GDF7))
- Alternative Name
- GDF-7 (GDF7 Products)
- Synonyms
- bmp12 Protein, gdf-7 Protein, gdf16 Protein, gdf16-A Protein, BMP12 Protein, GDF6/7 Protein, growth differentiation factor 7 S homeolog Protein, growth differentiation factor 7 Protein, gdf7.S Protein, GDF7 Protein, Gdf7 Protein
- Background
- GDF-7 belongs to the TGF-beta superfamily of growth and differentiation factors. It is expressed selectively by roof plate cells that are located in the developing embryonic central nervous system, and has been shown to influence the neuronal identity of cells within the central nervous system. GDF-7 has also been implicated in the formation, maintenance, and repair of certain cartilage and ligament tissue. Recombinant human GDF-7 is a 28 kDa disulfide linked homodimer containing two 129 amino acid residues.
- Gene ID
- 151449
- NCBI Accession
- NP_878248
- OMIM
- 61835232
- UniProt
- Q7Z4P5
- Pathways
- Tube Formation
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