S100A6 Protein (AA 1-90)

Catalog No. ABIN2181717

Product Details

Target: S100A6 (S100 Calcium Binding Protein A6 (S100A6))

Protein Type: Recombinant

Protein Characteristics: AA 1-90

Origin: Human

Source: Escherichia coli (E. coli)

Sequence: AA 1-90

Characteristics: This protein carries no "tag". The protein has a calculated MW of 10.2 kDa. The protein migrates as 10.2 kDa under reducing (R) condition (SDS-PAGE).

Purity: >95 % as determined by SDS-PAGE.

Sterility: 0.22 μm filtered

Endotoxin Level: Less than 1.0 EU per μg by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: PBS, pH 7.4

Handling Advice: Please avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).

Target Details

Target: S100A6 (S100 Calcium Binding Protein A6 (S100A6))

Alternative Name: S100A6 (S100A6 Products)

Synonyms: S100A6 Protein, 2A9 Protein, 5B10 Protein, CABP Protein, CACY Protein, PRA Protein, CALCYCLIN Protein, Cacy Protein, S100 calcium binding protein A6 Protein, uncharacterized LOC618256 Protein, S100 calcium binding protein A6 (calcyclin) Protein, S100A6 Protein, S100a6 Protein, LOC618256 Protein

Background: S100 calcium binding protein A6 (S100-A6) is also kown as 2A9, 5B10, CABP, CACY and PRA, is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. Most S100 proteins are disulfide-linked homodimer, and is normally present in cells derived from the neural crest, chondrocytes, macrophages, dendritic cells, etc. S100A6 may function in stimulation of Ca2+ -dependent insulin release, stimulation of prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of this gene have been implicated in melanoma. S100A6 has been shown to interact with S100B and SUGT1.

Molecular Weight: 10.2 kDa

Pathways: S100 Proteins