IFNAR1 Protein (AA 28-436) (Fc Tag)
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- Target See all IFNAR1 Proteins
- IFNAR1 (Interferon alpha/beta Receptor 1 (IFNAR1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 28-436
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This IFNAR1 protein is labelled with Fc Tag.
- Sequence
- AA 28-436
- Characteristics
- This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 73.8 kDa. The protein migrates as 110-120 kDa under reducing (R) condition (SDS-PAGE) due to Glycosylation.
- Purity
- >90 % as determined by SDS-PAGE.
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product IFNAR1 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Tris with Glycine, Arginine and NaCl, pH 7.5
- Handling Advice
- Please avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
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- Target
- IFNAR1 (Interferon alpha/beta Receptor 1 (IFNAR1))
- Alternative Name
- IFNAR1 (IFNAR1 Products)
- Synonyms
- ifnar1 Protein, IFNAR1 Protein, CD118 Protein, Ifar Protein, Ifnar Protein, Ifrc Protein, Infar Protein, AVP Protein, IFN-alpha-REC Protein, IFNAR Protein, IFNBR Protein, IFRC Protein, IFN-R-1 Protein, interferon alpha and beta receptor subunit 1 Protein, interferon-alpha/beta receptor alpha chain-like Protein, interferon (alpha and beta) receptor 1 Protein, interferon alpha/beta receptor 1 Protein, IFNAR1 Protein, ifnar1 Protein, Ifnar1 Protein, LOC609830 Protein
- Background
- Interferon alpha/beta receptor 1 ( IFNAR1) is also known as Cytokine receptor class-II member 1, Cytokine receptor family 2 member 1 (CRF2-1), Type I interferon receptor 1, IFNAR, which belongs to the type II cytokine receptor family. IFNAR1 /IFNAR contains four fibronectin type-III domains. IFNAR1 associates with IFNAR2 to form the type I interferon receptor. IFNAR1 is receptor for interferons alpha and beta. IFNAR1 can transduce IFNB signals without the help of IFNAR2, and not activating the Jak-STAT pathway.
- Molecular Weight
- 73.8 kDa
- NCBI Accession
- NP_000620
- Pathways
- JAK-STAT Signaling, Hepatitis C
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