Glypican 3 Protein (GPC3) (AA 25-559) (His tag)
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- Target See all Glypican 3 (GPC3) Proteins
- Glypican 3 (GPC3)
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 25-559
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Glypican 3 protein is labelled with His tag.
- Sequence
- AA 25-559
- Characteristics
- This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 61.7 kDa. The protein migrates as 40 kDa and 60-130 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation and associated via disulfide bonds.
- Purity
- >90 % as determined by SDS-PAGE.
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 0.1 EU per μg by the LAL method.
- Top Product
- Discover our top product GPC3 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Handling Advice
- Please avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
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- Target
- Glypican 3 (GPC3)
- Alternative Name
- Glypican 3 (GPC3 Products)
- Synonyms
- GPC3 Protein, sgb Protein, dgsx Protein, sdys Protein, sgbs Protein, oci-5 Protein, sgbs1 Protein, DGSX Protein, GTR2-2 Protein, MXR7 Protein, OCI-5 Protein, SDYS Protein, SGB Protein, SGBS Protein, SGBS1 Protein, Glypican-3 Protein, glypican 3 Protein, gpc3 Protein, GPC3 Protein, Gpc3 Protein
- Background
- Glypican-3 (GPC3) is also known as Intestinal protein OCI-5, GTR2-2, MXR7, which belongs to the glypican family. Glypican 3 / GPC-3 is highly expressed in lung, liver and kidney. Glypican-3 inhibits the dipeptidyl peptidase activity of DPP4. Glypican-3 may be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs, and also may play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function.
- Molecular Weight
- 61.7 kDa
- Pathways
- Glycosaminoglycan Metabolic Process
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