CDH6 Protein (AA 19-615) (His tag)
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- Target See all CDH6 Proteins
- CDH6 (K-Cadherin (CDH6))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 19-615
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CDH6 protein is labelled with His tag.
- Sequence
- AA 19-615
- Characteristics
- This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 67.2 kDa. The protein migrates as 90-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Purity
- >85 % as determined by SDS-PAGE.
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product CDH6 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Handling Advice
- Please avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C-8 °C), After reconstitution under sterile conditions for 1 month (4 °C-8 °C) or 3 months (-20 °C to -70 °C).
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- Target
- CDH6 (K-Cadherin (CDH6))
- Alternative Name
- Cadherin-6 (CDH6 Products)
- Synonyms
- KCAD Protein, K-cadherin Protein, cad6 Protein, cadherin-6 Protein, CAD6 Protein, c-cad6B Protein, cadherin 6 Protein, Cdh6 Protein, CDH6 Protein
- Background
- Cadherin-6 (CDH6) is also known as Kidney cadherin (K-cadherin or KCAD), is a a type II classical cadherin from the cadherin superfamily. Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells, cadherins may thus contribute to the sorting of heterogeneous cell types. CDH6 / KCAD contains five cadherin domains. CDH6 is highly expressed in brain, cerebellum, and kidney. Lung, pancreas, and gastric mucosa show a weak expression and also expressed in certain liver and kidney carcinomas.
- Molecular Weight
- 67.2 kDa & 63.4 kDa
- Pathways
- Cell-Cell Junction Organization
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